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1.2 – Population Mean Cosinor
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Figure 1.2–a : Population Mean Cosinor (Seriel Cosinor) tests : Abstract of tests for a fixed period (Triangular function of period 2Pi)
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1.3 : Population Mean Cosinor (Seriel Cosinor) – Confidence ellipse plot according to Gouthière and Jacquin
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Figure 1.3–a : Population Mean Cosinor : Confidence Ellipse plot (Rectangular function of period 2Pi, p=0.95 a=0.05)
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Figure 1.3–c : Population Mean Cosinor : Ellipse of confidence plot (Temperature/Alcoholic subjects period of 13.6 hours, p=0.95 a=0.05)
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1·4 : Population Mean Cosinor - Confidence ellipse according to Nelson et al, Bingham et al
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Figure 1.4–a : Population Mean Cosinor : Confidence Ellipse plot (Triangular function of period 2Pi, p=0.95 a=0.05)
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Figure 1.4–c : Population Mean Cosinor : Ellipse of confidence (Temperature/Alcoholic subjects period of 13.6 hours, p=0.95 a=0.05)
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1·5 : Population Mean Cosinor – Inverse Elliptic Spectral plot according to Gouthière
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Figure 1.5–a : Seriel Cosinor : Inverse elliptic spectral plot for an interval of given period and a level of probability (Triangular function of period 2Pi, p=0.95 a=0.05)
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1.6 : Population Mean Cosinor (Seriel Cosinor) – Percent Rhythm spectral plot
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Figure 1.6–a : Population Mean Cosinor (Seriel Cosinor) : Spectral plot of Percent Rhythm for a given interval of time and a given probability (Triangular function of period 2Pi, p=0.95 a=0.05)
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1.7 : Seriel Cosinor (Population Mean Cosinor) - Model and experimental points curves
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Figure 1.7–a : Population Mean Cosinor (Seriel Cosinor) : Model, experimental points and interpolation curves (Body temperature / Alcoholized subjects)
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1.8 : Population Mean Cosinor (Seriel Cosinor) - Residues Normal probability plot according to Chambers
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Figure 1.8–a : Seriel Cosinor (Population Mean Cosinor) - Residues Normal probability plot (Alcoholized subjects, period of 13.6, p=0.95 a=0.05)
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1.9 : Population Mean Cosinor (Seriel Cosinor) - Chronogram and confidence intervals
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Figure 1.9–a : Population Mean Cosinor - Chronogram and confidence intervals : phase and amplitude.
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2.1 : Single Cosinor - Tests for one period given
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Figure 2.1–a : Single Cosinor : Abstract of Cosinor Single tests (Triangular function of period 2Pi, p=0.95 a=0.05)
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2.2 : Single Cosinor – Ellipse of Confidence according to Gouthiere and Jacquin
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Figure 2.2–a : Single Cosinor : Ellipse of confidence (Triangular function of period 2Pi, p=0.95 a=0.05)
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2.3 : Single Cosinor – Confidence ellipse according to Nelson et al, Bingham et al
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Figure 2.3–a: Single Cosinor – Ellipse of Confidence according to Halberg et al.
(Triangular function of period 2Pi, p=0.95 a=0.05)
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2.4 : Single Cosinor – Spectral plot of Percent Rhythm
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Figure 2.4–a: Single Cosinor – Spectral plot of Percent Rhythm at an interval of a given period and at a given probability (Triangular function of period 2Pi p=0.95 a=0.05)
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2.5 : Single Cosinor – Model and experimental points curves
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Figure 2.5–a: Single Cosinor – Model and experimental points curves (Cosine function with 3 periods: 6, 12, 24)
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2.6 : Single Cosinor – Inverse Elliptic Spectral plot according to Gouthière
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Figure 2.6–a: Single Cosinor – Inverse Elliptic Spectral plot (Triangular function, p=0.95 a=0.05)
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2·13 – Single Cosinor – Chronogram and confidence intervals
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Figure 2·13-a : Single Cosinor – Chronogram and confidence intervals: CI of the phase and CI of the amplitude (Hamsters activity/ Anti-depressant)
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2.11 - Single Cosinor – Chronobiologic Window according to Halberg et al
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Figure 2.11 : Single Cosinor - Chronobiologic Window (Allows to detect the period by the study of the residues variance as a function of time) Example of a triangular function of period 2Pi.
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2.7 : Single Cosinor – Residues Normal Probability plot according to Chambers
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Figure 2.7–a: Single Cosinor – Normal probability plot on the residues of the Single Cosinor Model (Alcoholized subjects, Period of 24.7, p=0.95 a=0.05)
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2.8 : Single Cosinor – Complex Amplitude Demodulation plot according to Gouthière.
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Figure 2.8 : Single Cosinor – Complex Amplitude Demodulation plot (The aim is to verify the amplitude to be a constante)
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2.9 : Single Cosinor – Complex Phase Demodulation plot according to Gouthière
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Figure 2.9 : Single Cosinor – Complex Phase Demodulation plot (The aim is to verify the phase to be a constante)
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2.10 : Single Cosinor – Variance Homogeneity plot according to Draper and Smith
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Figure 2.10 : Single Cosinor – Variance Homogeneity plot.
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2·12 : Single Cosinor – Comparison of rhythms, comparison
of chronobiometric parameters according to Bingham et al
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Table 2.12 : Single Cosinor, comparison of rhythms (MESOR, Amplitude and Acrophase) of different series
for one period chosen (and a given probability) according to Bingham et al (Study of the Cortisol, period of
24.4 hours, p=0.95 a=0.05)
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3.1 : Time series analysis – Lag plot
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Figure 3.1-a : Lag Plot (Triangular function of period 2Pi and Rectangular function of period 2Pi, p=0.95 a=0.05)
A lag plot checks whether a data set or time series is random or not. Random data should not exhibit any
identifiable structure in the lag plot. Non-random structure in the lag plot indicates that the underlying data
are not random (
EDA Graphical Techniques 1.3.3.15. Lag Plot, Engineering Statistics Handbook) A complementary test of Ljung
and Box (Q test) check the assumption of "Independent Data".
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3.2 : Time series analysis – Autocorrelation plot
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Figure 3.2 : Autocorrelation plot (Triangular function of period 2Pi)
Autocorrelation plots (Box and Jenkins, pp. 28-32) are a commonly-used tool for checking randomness in a data set.
This randomness is ascertained by computing autocorrelations for data values at varying time lags. If random, such
autocorrelations should be near zero for any and all time-lag separations. If non-random, then one or more of the
autocorrelations will be significantly non-zero (
EDA Graphical Techniques 1.3.3.1. Autocorrelation Plot, Engineering Statistics Handbook) A confidence interval
is calculated and shows on the plot the band of randmoness (close to the zero x axis)
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3·14 – Time Series Analysis – Partial Autocorrelation Plot (PACF)
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Figure 3·14-1 : Partial Autocorrelation Plot (Triangular function of period 2Pi)
The data are not random. The PACF allows to verify is data are randomn. It is also use to determine the order
of an autoregressive model...
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3.3 : Time series analysis – Spectral Density plot according to Blochner
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Figure 3.3 : Spectral density plot (Triangular function of period 2Pi)
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3.4 : Time series analysis – Autospectral plot according to Jenkins and Watts
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Figure 3.4.1 : Autospectral plot (Hanning window) according to Jenkins and Watts (Triangular function of period 2Pi)
Figure 3.4.2 : Autospectral plot (Kaiser window) according to Jenkins and Watts (Triangular function of period 2Pi)
Figure 3.4.3 : Autospectral plot (Blackman-Harris window) according to Jenkins and Watts (Triangular function of period 2Pi)
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3.5 : Time series analysis – AutoPeriodogram plot according to Jenkins and Watts
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Figure 3.5 : Spectral Autoperiodogram according to Jenkins and Watts (Triangular function of period 2Pi)
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3.6 : Time series analysis – Periodogram plot according to Lomb and Scargle
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Figure 3.6 : Time series analysis – Periodogram plot according to Lomb et Scargle (Triangular function of period 2Pi)
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3.7 : Time series analysis – Discrete Fourier Transforms - Amplitude
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Figure 3.7.1 : Time series analysis – Discrete Fourier Transforms - Amplitude (Cosine function with periods 6, 12, 24, equispaced time data)
Figure 3.7.2 : Time series analysis – FFT - Amplitude (Cosine function with periods 6, 12, 24, equispaced time data)
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3.8 : Time series analysis – Fisher periodogram
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Figure 3.8 : Time series analysis – Fisher periodogram. The fundamental ray is tested (Hamster activity/Antidepressant)
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3·13 – Time series analysis – Fourier periodogram and Cumulative Fourier Periodogram (Schuster)
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Figure 3·13.1 : Time series analysis – Fourier Periodogram (Sum of cosine functions of periods 6, 12, 24)
Figure 3·13.2 : Time series analysis – Cumulative Fourier Periodogram (Sum of cosine functions of periods 6, 12, 24)
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3·15 – Time series analysis – Maximum Entropy Spectral Analysis (Burg MESA)
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Figure 3·15.1 : Time series analysis – MESA spectrum (Sum of cosine functions of periods 6, 12, 24)
Figure 3·15.2 : Time series analysis – MESA spectrum (Plasma Melatonin)
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3·7 – Time series analysis – Discrete Fourier Transforms - Amplitude
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Figure 3·7.1 : Time series analysis – Discrete Fourier Transforms - Amplitude (Cosine function of periods 6, 12, 24)
Figure 3·7.2 : ;Time series analysis – Fast Fourier Transforms- Amplitude (Cosine function of periods 6, 12, 24)
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3.9 : Normal probability plot according to Chambers
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Figure 3.9 : Normal probability plot of the experimental data (Temperature/Alcoholic subjects) The normal probability plot (Chambers 1983) is a graphical technique
for assessing whether or not a data set is approximately normally distributed. The data are plotted against a theoretical normal distribution in such a
way that the points should form an approximate straight line. Departures from this straight line indicate departures from normality...
( EDA Graphical Techniques 1.3.3.21. Normal Probability Plot, Engineering Statistics Handbook)
A complementary test of Komolgorov-Smirnov (K-S test) is used to test this assumption with a level of probability p (or risk 1 -p)
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3.10 : Scatter plot according to Chambers
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Figure 3.10 : Scatter plot of the experimental data with the linear trend (Temperature/Alcoholic subjects) A scatter plot (Chambers 1983) reveals relationships or association
between two variables. Such relationships manifest themselves by any non-random structure in the plot
( EDA Graphical Techniques 1.3.3.26. Scatter Plot, Engineering Statistics Handbook)
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3.11 : Run Sequence plot according to Chambers
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Figure 3.11 : Run Sequence plot. With run sequence plots, shifts in location and scale are typically quite
evident. Also, outliers can easily be detected ( EDA Graphical Techniques 1.3.3.25. Run Sequence Plot, Engineering Statistics Handbook)
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3·12 : Box plot according to Chambers
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Figure 3·12 : Box plot according to Chambers (Study of temperature with placebo). The Box plot
can provide answers to the following questions : 1) Is a factor significant ?, 2) Does the location differ between
subgroups ?, 3) Does the variation differ between subgroups ?, 4) Are there any outliers ?
The Box plot is an important EDA tool for determining if a factor has a significant effect on the response with
respect to either location or variation. The Box plot is also an effective tool for summarizing large quantities of
information ( EDA Graphical Techniques 1.3.3.7. Box Plot, Engineering Statistics Handbook)
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